Citrullinated Vimentin (R144) (139-159)-biotin Peptide

CAT N°: 37624
Price:

337.00 286.45

Citrullinated vimentin (R144) (139-159)-biotin peptide is a biotinylated version of a mono-citrullinated form of the cytoskeleton intermediate filament protein vimentin, which has been found in the synovial fluid of patients with rheumatoid arthritis.{55252} Vimentin is subject to citrullination by peptidyl arginine deiminase 2 (PAD2) under high calcium concentrations, which can occur during macrophage apoptosis.{64643,31884} Serum levels of immune complexes targeting citrullinated vimentin are increased in patients with rheumatoid arthritis and positive for anti-citrullinated protein antibodies (ACPAs).{66176} Serum and plasma levels of citrullinated vimentin are also increased in patients with lung cancer or idiopathic pulmonary fibrosis, respectively.{35094,35741} Cayman’s Citrullinated Vimentin (R144) (139-159)-biotin Peptide is intended for use in the detection of autoantibodies against vimentin citrullinated at R144.

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