Citicoline (sodium salt)

Citicoline (sodium salt)

CAT N°: 14629
Price:

From 48.00 40.80

Citicoline is an endogenous intermediate in the synthesis of phosphatidylcholine, the major phospholipid in eukaryotic cells.{23421} It also serves as a choline donor in the biosynthesis of the neurotransmitter acetylcholine. Citicholine demonstrates protective effects in cerebral ischemia, traumatic brain injury, and memory disorders.{23420} Exogenous administration of citicholine to rodents (500 mg/kg i.p. immediately after ischemia and at 3-h reperfusion) has been shown to stimulate the synthesis of phosphatidylcholine, sphingomyelin, and cardiolipin and to attenuate the release of arachidonic acid and the accumulation of ceramide.{23419}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • P’-[2-(trimethylammonio)ethyl] ester-cytidine 5′-(trihydrogen diphosphate)-inner, monosodium salt
  • Correlated keywords
    • 987-78-0 126832-19-7 Cytidine-5?-diphosphocholine CDP-choline cytidines diphosphate-choline lipids metabolisms ischemia neuroprotection synthesis phosphatidylcholine sphingomyelin cardiolipin sodium slats intermediates CDP cholines protective cerebral ischemias brains injuries memory memories disorders stimulates vascular diseases phospholipids neurosciences endogenous eukaryotic cerebral biosynthesis neurotransmitter acetylcholine arachidonic acids ceramides acticolin cebroton CerAxon cidifos citicoline IP 302 sodium strolin
  • Product Overview:
    Citicoline is an endogenous intermediate in the synthesis of phosphatidylcholine, the major phospholipid in eukaryotic cells.{23421} It also serves as a choline donor in the biosynthesis of the neurotransmitter acetylcholine. Citicholine demonstrates protective effects in cerebral ischemia, traumatic brain injury, and memory disorders.{23420} Exogenous administration of citicholine to rodents (500 mg/kg i.p. immediately after ischemia and at 3-h reperfusion) has been shown to stimulate the synthesis of phosphatidylcholine, sphingomyelin, and cardiolipin and to attenuate the release of arachidonic acid and the accumulation of ceramide.{23419}

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