<em>cis</em>-10-hydroxy Nortriptyline

cis-10-hydroxy Nortriptyline

CAT N°: 36659
Price:

From 128.00 108.80

cis-10-hydroxy Nortriptyline is an active metabolite of the tricyclic antidepressants amitriptyline (Item No. 15881) and nortriptyline (Item No. 15904).{61943,61944} It is formed from amitriptyline and nortriptyline by the cytochrome P450 (CYP) isoform CYP2D6.{61943} cis-10-hydroxy Nortriptyline inhibits norepinephrine reuptake in rat cortical slices (EC50 = 160 nM).{61944}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (5Z)-10,11-dihydro-5-[3-(methylamino)propylidene]-5H-dibenzo[a,d]cyclohepten-10-ol
  • Correlated keywords
    • 37439-87-5 anti-depressant OHNT 10(Z)OHNT Hydroxynortriptyline P-450 CYP-2D6 CYP2D-6 OH-NT
  • Product Overview:
    cis-10-hydroxy Nortriptyline is an active metabolite of the tricyclic antidepressants amitriptyline (Item No. 15881) and nortriptyline (Item No. 15904).{61943,61944} It is formed from amitriptyline and nortriptyline by the cytochrome P450 (CYP) isoform CYP2D6.{61943} cis-10-hydroxy Nortriptyline inhibits norepinephrine reuptake in rat cortical slices (EC50 = 160 nM).{61944}

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