Ciprofloxacin (hydrochloride)

Territorial Availability: Available through Bertin Technologies only in France

• Synonyms
  • 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid, monohydrochloride
• Correlated keywords
  • 85721-33-1 86393-32-0 Adiflox Alcon Cilox BAY-o 9867 Bacquinor Bactiflox Baflox Baycip Belmacina Bernoflox Cetraxal Ciflodal Ciflox Cifloxin Cifran Cilab Ciloxan Cimogal Ciplox Ciploxx Ciplus Ciprecu Ciprinol Cipro Cipro (pharmaceutical) Cipro optic Ciprobay Ciprobay Uro Ciprobid Ciprobiotic Ciprocin Ciprocinol Ciprodar Ciprofar Ciproflox Ciprofloxacin hydrochloride Ciprogis Ciprok Ciprolin Ciprolon Cipromycin Ciproquinol Ciprowin Ciproxan Ciproxin Ciproxine Ciriax Citopcin Cixan Corsacin Cosflox Cycin Cyprobay Eni Estecina Fimoflox Ipiflox Kenzoflex Loxan Medociprin Microrgan Mitroken NSC 620634 Nivoflox Opthaflox Probiox Proflaxin Proflox Proksi 250 Proksi 500 Quinolide Quintor Rancif Ringoran Roxytal Septicide Serviflox Sipro 250 Sophixin Ofteno Spitacin Superocin Unex Uniflox Zoxan Zumaflox Staphylococcus Pseudomonas Neisseria Helicobacter Escherichia Proteus Klebsiella Pseudomonas NSC620634
• Product Overview:
  Ciprofloxacin is a fluoroquinolone antibiotic.{22833} It is active against a variety of Gram-positive and Gram-negative bacteria in vitro, including S. aureus, L. monocytogenes, P. aeruginosa, Legionella, N. gonorrhoeae, and H. pylori (MIC50s = 0.004-1 µg/ml).{32846} It is also active against clinical isolates of Bacteroides, Fusobacterium, Eubacterium, Actinomyces, Peptococcus, Peptostreptococcus, and Streptococcus in vitro (MIC50s = 0.5-2 µg/ml).{32013} Ciprofloxacin inhibits S. aureus DNA gyrase and topoisomerase IV (IC50s = 13.5 and 5.76 µg/ml, respectively).{27493} It reduces mortality in mouse models of intraperitoneal E. coli, P. vulgaris, K. pneumoniae, P. aeruginosa, and S. aureus infection (ED90-100s = 1-5, 2.5-5, 5-10, 20-40, and 80 mg/kg, respectively) and prevents mortality in a mouse model of subcutaneous S. typhimurium infection at 10 mg/kg.{39940,39939} Formulations containing ciprofloxacin have been used in the treatment of bacterial infections.