Chrodrimanin B

Chrodrimanin B

CAT N°: 27585
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322.00 273.70

Chrodrimanin B is a meroterpenoid fungal metabolite that has been found in Talaromyces species.{48232} It has insecticidal activity against third instar silkworm larvae (LD50 = 10 ?g/g of diet). Chrodrimanin B selectively inhibits the silkworm GABA receptor RDL (IC50 = 1.13 nM) over human ?1?2?2 subunit-containing GABA receptors (IC50 = 1.48 ?M).{48233} The structure of thailandolide B, originally described as a C-9 epimer of chrodrimanin B, was revised in 2012 and is identical to that of chrodrimanin B.{48232}

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