Chk2 Inhibitor II

Chk2 Inhibitor II

CAT N°: 17552
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From 48.00 40.80

Chk2 inhibitor II is a selective, ATP-competitive inhibitor of the DNA damage control kinase, checkpoint kinase 2 (IC50 = 15 nM).{28503} It has been shown to prevent apoptosis in human T-cells exposed to ionizing radiation (EC50 = 3-7.6 µM).{28503} This compound has been used to target the role of Chk2 in cellular signaling in response to DNA damage.{28504}

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