CHIR090

CHIR090

CAT N°: 22256
Price:

From 85.00 72.25

CHIR090 is an antibiotic that inhibits LpxC, a deacetylase involved in the biosynthesis of LPS lipid A, with Ki values of 1-1.7 nM in A. aeolicus.{38249} It is active against Gram-negative bacteria with MIC values of 0.05, 0.78, and 0.10-6.25 mg/ml for E. coli, P. aeruginosa, and various B. multivorans (II) strains, respectively.{38247,38248} It is comparable in strength to ciprofloxacin (Item No. 14286) in disc assays.{38249}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • N-[(1S,2R)-2-hydroxy-1-[(hydroxyamino)carbonyl]propyl]-4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]-benzamide
  • Correlated keywords
    • CHIR-090 anti-biotic lipopolysaccharide aquifex escherichia pseudomonas burkholderia
  • Product Overview:
    CHIR090 is an antibiotic that inhibits LpxC, a deacetylase involved in the biosynthesis of LPS lipid A, with Ki values of 1-1.7 nM in A. aeolicus.{38249} It is active against Gram-negative bacteria with MIC values of 0.05, 0.78, and 0.10-6.25 mg/ml for E. coli, P. aeruginosa, and various B. multivorans (II) strains, respectively.{38247,38248} It is comparable in strength to ciprofloxacin (Item No. 14286) in disc assays.{38249}

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