Cercosporin

Cercosporin

CAT N°: 22175
Price:

From 92.00 78.20

Cercosporin is a pigmented phytotoxin isolated from the fungus C. kikuchii that produces reactive oxygen species in plant hosts leading to cellular damage.{37038,37041} It exhibits light-activated cytotoxic effects in vitro with cytotoxic concentration (CC50) values of 241, 282, and 174 nM in HeLa, A432, and MCF-7 cells, respectively.{37040} It is a selective inhibitor of PKC (IC50 = 600-1,300 nM) with no activity on PKA or PPK at concentrations over 180 µM.{37039}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (13bR)-6,12-dihydroxy-8,9-bis[(2R)-2-hydroxypropyl]-7,10-dimethoxy-perylo[1,12-def]-1,3-dioxepin-5,11-dione
  • Correlated keywords
    • CGP049090 NSC153111 cercsopsorium cercospora ROS A-432 MCF7 protein kinase C A
  • Product Overview:
    Cercosporin is a pigmented phytotoxin isolated from the fungus C. kikuchii that produces reactive oxygen species in plant hosts leading to cellular damage.{37038,37041} It exhibits light-activated cytotoxic effects in vitro with cytotoxic concentration (CC50) values of 241, 282, and 174 nM in HeLa, A432, and MCF-7 cells, respectively.{37040} It is a selective inhibitor of PKC (IC50 = 600-1,300 nM) with no activity on PKA or PPK at concentrations over 180 µM.{37039}

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