24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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Cepharanthine is a biscoclaurine alkaloid extracted from S. cepharantha that is cationic and amphipathic and has been reported to decrease the fluidity of biological membranes.{31428} It exhibits antiparasitic, antimalarial, antiviral, anti-inflammatory, antimetastatic, and anticancer activities in various cell and animal models.{31428,31426,31429} Cepharanthine can decrease LPS-stimulated expression of TNF-?, IL-6, and IL-1? in macrophages and prevent the activation of NF-?B, ERK, JNK, and p38 MAPK.{31427} It has also been shown to inhibit cell and tumor growth, inducing G1 phase cell cycle arrest and apoptosis, and decreasing expression of STAT3, Bcl-xL, c-Myc, and cyclin D1 in osteosarcoma models.{31425}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 g, 100 mg, 50 mg, 500 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 481-49-2 |
| Molecular formula | C37H38N2O6 |
| Smiles | CN1CCC(C=C(OCO2)C2=C3OC4=C(OC)C=C(CCN(C)[C@]5([H])CC6=CC=C(OC)C7=C6)C5=C4)=C3[C@]1([H])CC8=CC=C(O7)C=C8 |
| Molecular weight | 606,7 |
| Custom code | 2922.19 |
| Formulation | A crystalline solid |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
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