CD437

CD437

CAT N°: 71610
Price:

From 129.00 109.65

CD437 is the prototypical adamantyl arotinoid of the retinoid-related molecule family that acts as a selective agonist of retinoic acid receptor (RAR)? (Kds = 6.5 ?M, 2.5 ?M, and 77 nM for RAR?, ?, and ?, respectively).{24739,24736} CD437 is cytotoxic to the acute myeloid leukemia cell line NB4 (EC50 = 0.17 ?M), inducing DNA damage by producing DNA double strand breaks.{24735} CD437 also induces cell cycle arrest and apoptosis in various other cancer cells including melanoma, breast, non-small lung, and prostate cancer cells through RAR-dependent and -independent signaling pathways.{24737,24738}

We also advise you

TAF 10 Peptide

TAF 10 Peptide

TAF10 is one of many protein factors or coactivators associated with RNA polymerase II activity.{16903} One vial of this peptide...

€191.00
View