CCT031374 (hydro<wbr/>bromide)

CCT031374 (hydrobromide)

CAT N°: 32866
Price:

From 54.00 45.90

CCT031374 is an inhibitor of ?-catenin/transcription factor (TCF) complex signaling.{57366} It inhibits TCF-dependent transcription induced by expression of ?N-?-catenin, a constitutively active, stabilized form of ?-catenin, but not expression of a constitutively active TCF-VP16 fusion protein in reporter assays at 30 µM. CCT031374 (80 µM) induces apoptosis in, and inhibits growth of, HCT116 colon cancer cells.

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