CAY10770

CAY10770

CAT N°: 31216
Price:

From 92.00 78.20

CAY10770 is an inhibitor of the cytochrome P450 (CYP) isoform CYP4Z1 (IC50 = 5.9 µM).{57196} It is selective for CYP4Z1 over CYP4A11, CYP4F2, CYP4F3a, CYP4F3b (IC50s = 187-282 µM) but does inhibit CYP4F8 and CYP4F12 (IC50s = 167 and 91 µM, respectively). CAY10770 (3 µM) inhibits the production of 14(15)-EET, 19-HETE, and 14(15)-DiHET by 83, 86, and 80%, respectively, in T47D breast cancer cells expressing CYP4Z1.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 8-(1H-benzotriazol-1-ylamino)-octanoic acid
  • Correlated keywords
    • CAY 10770 P 450 4Z1 4A11 4F2 4F3a 4F3b 4F8 4F12 14(15)EET 19HETE 14(15)DiHET T47 D
  • Product Overview:
    CAY10770 is an inhibitor of the cytochrome P450 (CYP) isoform CYP4Z1 (IC50 = 5.9 µM).{57196} It is selective for CYP4Z1 over CYP4A11, CYP4F2, CYP4F3a, CYP4F3b (IC50s = 187-282 µM) but does inhibit CYP4F8 and CYP4F12 (IC50s = 167 and 91 µM, respectively). CAY10770 (3 µM) inhibits the production of 14(15)-EET, 19-HETE, and 14(15)-DiHET by 83, 86, and 80%, respectively, in T47D breast cancer cells expressing CYP4Z1.

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