CAY10576

CAY10576

CAT N°: 10011249
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From 68.00 57.80

CAY10576 is a multi-kinase inhibitor.{16237,68151,65374} It inhibits TANK-binding kinase 1 (TBK1), polo-like kinase 1 (Plk1), and IKK? (IC50s =0.093, 0.63, and 0.79 µM, respectively) and is selective for these kinases over IKK?, Aurora B kinase, and cyclin-dependent kinase 2 (Cdk2; IC50s = 5, >5.32 and >30 µM, respectively).{16237,68151,65374} CAY10576 also inhibits Rho-associated kinase1 (ROCK1) and ROCK2 (IC50s = 1.8 and 0.04 µM, respectively).{65375}

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