Carbadox

Carbadox

CAT N°: 24903
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Carbadox is a broad-spectrum antimicrobial agent that inhibits the growth of bacteria, including S. typhimurium strains (MICs = 3.6-14.3 µM under aerobic conditions) and S. hyodysenteriae isolates from pigs (MIC90 = 0.006 ?g/ml).{42137,42138} It also inhibits the growth of C. hyointestinalis, C. mucosalis, and C. coli isolates from pigs (MIC90s = ?0.125-1 ?g/ml) and of spirochete bacterial isolates from dogs (MIC90s = In vivo, carbadox is protective and effective against S. hyodysenteriae infection in mice (ED50s = 7.7 and 5 mg/kg, respectively).{42138} It is mutagenic and induces DNA breaks and chromosomal damage to Vero cells at a concentration of 10 ?g/ml.{42141}

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