Calycosin 7-O-?-D-Glucoside

Calycosin 7-O-?-D-Glucoside

CAT N°: 25095
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From 55.00 46.75

Calycosin 7-O-?-D-glucoside is an isoflavone glycoside that has been isolated from A. mongholicus and A. membranaceus and has antioxidant, anti-inflammatory, and neuroprotective biological activities.{43143,43144,43145} It scavenges 34.5% of generated 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals compared to a vehicle control when used at a concentration of 100 ?g/ml in a cell-free assay.{43143} Calycosin 7-O-?-D-glucoside (10 ?g/ml) inhibits cytotoxicity, intracellular reactive oxygen species (ROS) production, and cytoskeletal defects induced by LPS in human umbilical vein endothelial cells (HUVECs).{43144} In vivo, calycosin 7-O-?-D-glucoside (26.8 mg/kg) reduces brain infarct volume in a rat model of ischemia-reperfusion injury induced by middle cerebral artery occlusion (MCAO).{43145}

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