C2 L-<em>erythro</em> Ceramide (d18:1/2:0)

C2 L-erythro Ceramide (d18:1/2:0)

CAT N°: 24387
Price:

277.00 235.45

C2 L-erythro Ceramide is a bioactive sphingolipid and a cell-permeable analog of naturally occurring ceramides.{37337} It stimulates cholesterol efflux in CHO cells expressing the human ABCA1 receptor when used at a concentration of 10 ?M, however, this efflux is >50% less than that stimulated by C2 ceramide (Item No. 62510). C2 L-erythro Ceramide also induces cell cycle arrest in the G0G1 phase and a 50-fold increase in sphingosine accumulation as well as inhibits growth of HL-60 leukemia cells.{37336,37339} [Matreya, LLC. Catalog No. 1847]

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • N-[(1R,2S,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-acetamide
  • Correlated keywords
    • C-2 chinese hamster ovary ABCA-1 HL60
  • Product Overview:
    C2 L-erythro Ceramide is a bioactive sphingolipid and a cell-permeable analog of naturally occurring ceramides.{37337} It stimulates cholesterol efflux in CHO cells expressing the human ABCA1 receptor when used at a concentration of 10 ?M, however, this efflux is >50% less than that stimulated by C2 ceramide (Item No. 62510). C2 L-erythro Ceramide also induces cell cycle arrest in the G0G1 phase and a 50-fold increase in sphingosine accumulation as well as inhibits growth of HL-60 leukemia cells.{37336,37339} [Matreya, LLC. Catalog No. 1847]

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