C16 Lactosyl<wbr/>ceramide-d<sub>3</sub> (d18:1/16:0-d<sub>3</sub>)

C16 Lactosylceramide-d3 (d18:1/16:0-d3)

CAT N°: 24625
Price:

842.00 715.70

C16 Lactosylceramide-d3 (d18:1/16:0-d3) is intended for use as an internal standard for the quantification of C16 lactosylceramide (Item No. 24352) by GC- or LC-MS. C16 Lactosylceramide is an endogenous bioactive sphingolipid.{41044} It forms membrane microdomains with Lyn kinase and the ?i subunits of inhibitory G protein-coupled receptors (GPCRs), suggesting a role in cell signaling. Plasma levels of C16 lactosylceramide are elevated in insulin-resistant cattle.{38685} C16 Lactosylceramide is also upregulated in a mouse model of Niemann-Pick type C1 disease, a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder.{40751} As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 1534]

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • N-[(1S,2R,3E)-1-[[(4-O-?-D-galactopyranosyl-?-D-glucopyranosyl)oxy]methyl]-2-hydroxy-3-heptadecen-1-yl]-hexadecanamide-d3
  • Correlated keywords
    • 2097249-92-6 C-16 1 lactosyl-ceramide ?-i deuterated deuterium
  • Product Overview:
    C16 Lactosylceramide-d3 (d18:1/16:0-d3) is intended for use as an internal standard for the quantification of C16 lactosylceramide (Item No. 24352) by GC- or LC-MS. C16 Lactosylceramide is an endogenous bioactive sphingolipid.{41044} It forms membrane microdomains with Lyn kinase and the ?i subunits of inhibitory G protein-coupled receptors (GPCRs), suggesting a role in cell signaling. Plasma levels of C16 lactosylceramide are elevated in insulin-resistant cattle.{38685} C16 Lactosylceramide is also upregulated in a mouse model of Niemann-Pick type C1 disease, a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder.{40751} As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 1534]

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