Amyloid-? (1-8, A2V) Peptide
Amyloid-? (1-8, A2V) Peptide
Amyloid-? (1-8, A2V) is a truncated form of amyloid-? (A?) that contains a valine to alanine substitution at position 2...
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From €146.00 €124.10
From €146.00 €124.10
Brivudine is a thymidine analog and inhibitor of herpes simplex virus 1 (HSV-1) and varicella-zoster virus (VZV) viral replication.{42575,53248} Following conversion to a 5′-triphosphate form by viral kinases, brivudine is incorporated into viral DNA, inhibiting viral DNA polymerases and inducing strand breakage.{53248} Brivudine (0.02-0.04 ?g/ml) inhibits VZV replication in primary human fibroblasts and inhibits cytopathogenic effects of the KOS HSV-1 strain in a panel of cell lines (MIC50s = 0.007-0.4 ?g/ml).{42575,53249} It selectively inhibits cytopathogenicity induced by HSV-1 strains over HSV-2, vaccinia virus, vesicular stomatitis virus, or deoxythymidine kinase-deficient HSV-1 strains in E6SM cells (MIC50s = 0.02, 2-10, 7, >400, and 40 ?g/ml, respectively).{42575} Brivudine (5 and 15 mg/kg twice per day) increases survival in a mouse model of disseminated HSV-1 infection.
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 g, 100 mg, 250 mg, 500 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 69304-47-8 |
| Molecular formula | C11H13BrN2O5 |
| Smiles | Br/C=C/C(C(N1)=O)=CN([C@@]2([H])C[C@H](O)[C@@H](CO)O2)C1=O |
| Molecular weight | 333,1 |
| Custom code | 2934.99 |
| Formulation | A crystalline solid |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
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