BQ-3020 (trifluoroacetate salt)

BQ-3020 (trifluoroacetate salt)

CAT N°: 34014
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From 134.00 113.90

BQ-3020 is a peptide endothelin type B (ETB) receptor agonist.{58930} It selectively binds to ETB over ETA receptors (IC50s = 0.07 and 940 nM, respectively) and induces inositol triphosphate formation and calcium mobilization in isolated bovine carotid artery endothelial cells.{58930,58932} BQ-3020 increases or decreases renal perfusion pressure in Dahl salt-resistant or -sensitive rats, respectively.{58933} It decreases the production of nitric oxide (NO) and induces vasoconstriction in a rat model of diet-induced hypercholesterolemia.

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