BMS-5

BMS-5

CAT N°: 21072
Price:

From 72.00 61.20

BMS-5 is a potent inhibitor of activated LIM domain kinases LIMK1 and LIMK2 with IC50 values of 7 and 8 nM, respectively.{32445} LIMK1 and LIMK2 participate in signal pathways affecting actin dynamics by deactivating cofilin.{32443,32444} This compound can be used to study the role of activated LIMK isoforms in the signaling of Rho family GTPases to cytoskeletal proteins, including cofilin.

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