BMS 270394

BMS 270394

CAT N°: 35576
Price:

168.00 142.80

BMS 270394 is an agonist of retinoic acid receptor ? (RAR?; EC50 = 30 nM in a transactivation assay) and the active enantiomer of BMS 189961 (Item No. 29380).{52154} It is selective for RAR? over RAR? (EC50 = 400 nM) and is inactive at RAR?. BMS 270394 synergizes with paclitaxel (Item No. 10461) to inhibit the growth of MCF-7 breast and OVCAR-3 ovarian cancer, as well as SqCC/Y1 head and neck squamous cell carcinoma, cells.{61883}

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