<em>bis</em>-ANS (potassium salt)

bis-ANS (potassium salt)

CAT N°: 21820
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From 48.00 40.80

bis-ANS is a high-affinity non-covalent extrinsic fluorescent dye used to analyze protein conformation.{33937} Its predominant interaction with proteins is through its hydrophobic phenyl and naphthyl rings.{33952} bis-ANS has an excitation maxima of 390 nm.{14908} It has an emission maximum of 523 nm when free in solution but undergoes a blue shift with an increase in fluorescence intensity when bound to protein; for example, when bound to intestinal fatty acid binding protein (FAPB2) it has emission maxima of 484-496 nm. bis-ANS has been used to label mechanically damaged neurons in acute brain slices.{33940} It also potently inhibits microtubule assembly.{33938,33939}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 4,4′-bis(phenylamino)-[1,1′-binaphthalene]-5,5′-disulfonic acid, dipotassium salt
  • Correlated keywords
    • 63741-13-9 noncovalent bisANS anilinonaphthalenesulfonate
  • Product Overview:
    bis-ANS is a high-affinity non-covalent extrinsic fluorescent dye used to analyze protein conformation.{33937} Its predominant interaction with proteins is through its hydrophobic phenyl and naphthyl rings.{33952} bis-ANS has an excitation maxima of 390 nm.{14908} It has an emission maximum of 523 nm when free in solution but undergoes a blue shift with an increase in fluorescence intensity when bound to protein; for example, when bound to intestinal fatty acid binding protein (FAPB2) it has emission maxima of 484-496 nm. bis-ANS has been used to label mechanically damaged neurons in acute brain slices.{33940} It also potently inhibits microtubule assembly.{33938,33939}

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