Bicyclo Prostaglandin E<sub>2</sub>

Bicyclo Prostaglandin E2

CAT N°: 14530
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122.00 103.70

Bicyclo prostaglandin E2 (bicyclo PGE2) is a stable breakdown product of PGE2 (Item No. 14010) and 13,14-dihydro-15-keto PGE2 (Item No. 14650). Bicyclo PGE2 is a stable, base-catalyzed transformation product of 13,14-dihydro-15-keto PGE2. 13,14-dihydro-15-keto PGE2 itself is a metabolite of PGE2 found in human plasma at a median level of 20-25 pg/ml.{182,4383} Due to the inherent instability of 13,14-dihydro-15-keto PGE2, it is advisable to quantify it as bicyclo PGE2 to estimate PGE2 biosynthesis or metabolism in vivo.{2571,581}

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