Histone H2A (Xenopus, recombinant)
Histone H2A (Xenopus, recombinant)
Histone H2A is a core histone that forms a dimer with histone H2B.{46631} Two histone H2A/H2B dimers form an octameric...
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€48.00 €40.80
€48.00 €40.80
BIBR 1532 is a mixed-type non-competitive inhibitor of telomerase (IC50 = 93 nM) that has little effect on several mammalian DNA and RNA polymerases, bacterial DNA helicase, or HIV-1 reverse transcriptase.{27220,27216,27218} It specifically targets the telomerase reverse transcriptase catalytic subunit, TERT.{27216,27217} Through its effects on telomerase, BIBR 1532 induces senescence or apoptosis in cancer cells.{27220,27219} Apoptosis in triple negative breast cancer cells induced by BIBR 1532 is potentiated by glucose restriction.{27219}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 mg, 10 mg, 5 mg, 50 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 321674-73-1 |
| Molecular formula | C21H17NO3 |
| Smiles | C/C(C1=CC2=CC=CC=C2C=C1)=CC(NC3=C(C=CC=C3)C(O)=O)=O, C/C(C1=CC2=CC=CC=C2C=C1)=CC(NC3=C(C=CC=C3)C(O)=O)=O, C/C(C1=CC2=CC=CC=C2C=C1)=CC(NC3=C(C=CC=C3)C(O)=O)=O, C/C(C1=CC2=CC=CC=C2C=C1)=CC(NC3=C(C=CC=C3)C(O)=O)=O |
| Molecular weight | 331,4 |
| Custom code | 2922.19 |
| Formulation | A crystalline solid |
| Purity | ≥95% |
| UNSPSC code | 12352100 |
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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
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Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.
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