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BIBF 1202 is an active metabolite of the VEGFR, FGFR, and PDGFR inhibitor BIBF 1120 (nintedanib; Item No. 11022).{20204,47489} It is formed from BIBF 1120 by intracellular esterases.{20204} BIBF 1202 inhibits VEGFR2 with an IC50 value of 62 nM.
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 mg, 10 mg, 5 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 894783-71-2 |
| Molecular formula | C30H31N5O4 |
| Smiles | CN(C(CN1CCN(C)CC1)=O)C(C=C2)=CC=C2N/C(C3=CC=CC=C3)=C4C(NC5=C4C=CC(C(O)=O)=C5)=O, CN(C(CN1CCN(C)CC1)=O)C(C=C2)=CC=C2N/C(C3=CC=CC=C3)=C4C(NC5=C4C=CC(C(O)=O)=C5)=O, CN(C(CN1CCN(C)CC1)=O)C(C=C2)=CC=C2N/C(C3=CC=CC=C3)=C4C(NC5=C4C=CC(C(O)=O)=C5)=O |
| Molecular weight | 525,6 |
| Custom code | 2933.59 |
| Formulation | A solid |
| Purity | ≥95% |
| UNSPSC code | 12352100 |
Cayman Chemical’s mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.
Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
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Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.
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