Histone H2A (Xenopus, recombinant)
Histone H2A (Xenopus, recombinant)
Histone H2A is a core histone that forms a dimer with histone H2B.{46631} Two histone H2A/H2B dimers form an octameric...
€818.00
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From €60.00 €51.00
Berbamine is a bisbenzylisoquinoline alkaloid that has been found in B. aristata and has diverse biological activities.{69057,69058,69059,69060} It induces apoptosis and autophagy in, and is cytotoxic to, HT-29 cells when used at concentrations ranging from 3 to 100 µM.{69057} Berbamine reduces viral infectivity in Vero E6 cells infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; IC50 = 2.35 µM) and decreases cell surface levels of angiotensin-converting enzyme 2 (ACE2) in Huh7 cells when used at a concentration of 10 µM.{69058} In vivo, berbamine (25 and 50 mg/kg) reduces hepatic lipid accumulation and inflammatory cytokine levels, serum and hepatic triglyceride and total cholesterol levels, and serum aspartate aminotransferase (AST) and alanine transaminase (ALT) levels in a mouse model of ethanol-induced liver injury.{69059} It also protects against myocardial apoptosis, mitochondrial dysfunction, and lipid peroxidation in a rat model of myocardial infarction induced by isoproterenol (Item No. 15592).{69060}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 1 g, 250 mg, 500 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 6078-17-7 |
| Molecular formula | C37H40N2O6 • 2HCl |
| Smiles | COC1=C2C3=C(CCN([C@]3([H])CC4=CC=C(O)C(OC5=CC=C(C[C@@]6([H])C7=CC(O2)=C(C=C7CCN6C)OC)C=C5)=C4)C)C=C1OC.Cl.Cl |
| Molecular weight | 681,7 |
| Custom code | 2933.49 |
| Formulation | A solid |
| Purity | ≥95% |
| UNSPSC code | 12352100 |
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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
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Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.
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