Benzoyl-Coenzyme A (sodium salt)

Benzoyl-Coenzyme A (sodium salt)

CAT N°: 27859
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Benzoyl-coenzyme A (benzoyl-CoA) is an intermediate in the microbial metabolism of aromatic compounds.{49121,49122} It can be produced via anaerobic metabolism of benzoate, toluene, and phenylalanine, among others, in the environment as well as the gut microbiome.{49121} In proteobacteria, conversion of benzoate to benzoyl-CoA by a benzoate-CoA ligase can occur under both aerobic and anaerobic conditions.{49122} Benzoyl-CoA is also a precursor in the biosynthesis of the antibiotic enterocin (Item No. 20592) in Salinospora.{49123} Benzoyl-CoA has been used as a substrate to measure the enzyme kinetics of human recombinant glycine N-acyltransferase (GLYAT), which catalyzes the formation of hippuric acid from benzoyl-CoA and glycine.{49124}

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