Benastatin B

Benastatin B

CAT N°: 32893
Price:

853.00 725.05

Benastatin B is a polyketide synthase-derived benastatin that has been found in Streptomyces and has diverse biological activities.{63002,61436,61437} It inhibits glutathione S-transferase (GST; Ki = 3.7 µM for the rat liver enzyme).{61436} Benastatin B also inhibits the transglycosylase activity of A. baumannii, C. difficile, E. coli, and S. aureus recombinant penicillin-binding proteins (PBPs; IC50s = 16, 53.3, 30.7, and 31.6 µM, respectively).{61437} It is active against several bacteria, including methicillin-resistant S. aureus (MRSA; MIC = 3.12 µg/ml).{61436}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 5,6,8,13-tetrahydro-1,7,9,11-tetrahydroxy-13,13-dimethyl-8-oxo-3-pentyl-benzo[a]naphthacene-2-carboxylic acid
  • Correlated keywords
    • Acinetobacter Clostridioides Escherichia Staphylococcus
  • Product Overview:
    Benastatin B is a polyketide synthase-derived benastatin that has been found in Streptomyces and has diverse biological activities.{63002,61436,61437} It inhibits glutathione S-transferase (GST; Ki = 3.7 µM for the rat liver enzyme).{61436} Benastatin B also inhibits the transglycosylase activity of A. baumannii, C. difficile, E. coli, and S. aureus recombinant penicillin-binding proteins (PBPs; IC50s = 16, 53.3, 30.7, and 31.6 µM, respectively).{61437} It is active against several bacteria, including methicillin-resistant S. aureus (MRSA; MIC = 3.12 µg/ml).{61436}

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