24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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€92.00 €78.20
BD 1063 is an antagonist of sigma-1 (?1) receptors (Ki = 9 nM).{39221} It is selective for ?1 receptors over ?2 (Ki = 449 nM) and serotonin 5-HT2 receptors (Ki = 2,552 nM), as well as opioid, dopamine D2, PCP, serotonin 5-HT1, ?1-, ?2-, and ?-adrenergic receptors where it has Ki values of greater than 10 µM. BD 1063 (30 mg/kg) inhibits locomotor activity induced by cocaine (Item Nos. 16186 | ISO60176) in mice and decreases ethanol intake in a dose-dependent manner in two rat models of excessive drinking when administered at doses ranging from 3.3 to 11 mg/kg.{39221,37408}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 10 mg, 5 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 206996-13-6 |
| Molecular formula | C13H18Cl2N2 • 2HCl |
| Smiles | ClC1=C(Cl)C=CC(CCN2CCN(C)CC2)=C1.Cl.Cl |
| Molecular weight | 346,1 |
| Custom code | 2933.59 |
| Formulation | A crystalline solid |
| Purity | ≥95% |
| UNSPSC code | 12352100 |
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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
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