BC-11-38

BC-11-38

CAT N°: 20167
Price:

From 102.00 86.70

BC-11-38 is a potent and selective phosphodiesterase (PDE) 11 inhibitor (IC50s = 0.28 µM and >100 µM for PDE11 and PDE1-10, respectively).{33958} Gene association studies suggested that PDE11 was involved in adrenal function, and in H295R human adrenocortical cells, BC-11-38 increased cAMP and cortisol levels and activating transcription factor 1 (ATF-1) phosphorylation.{33959,33960,33958}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 6,7-dihydro-3-phenyl-2-(propylthio)-thieno[3,2-d]pyrimidin-4(3H)-one
  • Correlated keywords
    • BC1138 BC11-38 PDE-11 1 10 ATF-1 cyclic adenosine 3′,5′-monophosphate
  • Product Overview:
    BC-11-38 is a potent and selective phosphodiesterase (PDE) 11 inhibitor (IC50s = 0.28 µM and >100 µM for PDE11 and PDE1-10, respectively).{33958} Gene association studies suggested that PDE11 was involved in adrenal function, and in H295R human adrenocortical cells, BC-11-38 increased cAMP and cortisol levels and activating transcription factor 1 (ATF-1) phosphorylation.{33959,33960,33958}

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