Balsalazide

Balsalazide

CAT N°: 18680
Price:

From 85.00 72.25

Balsalazide is a prodrug form of 5-aminosalicylic acid (5-ASA; Item No. 70265).{48536} It is cleaved by bacterial azoreductases in the intestinal lumen to release 5-ASA. Balsalazide (600 mg/kg per day) decreases IL-2 levels and increases IL-6 levels in the serum and colonic mucosa membrane, as well as decreases micro- and macroscopic colonic damage, in a rat model of colitis induced by 2,4-dinitrochlorobenzene (DNCB).{48537} Formulations containing balsalazide have been used in the treatment of ulcerative colitis.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 5-[(1E)-2-[4-[[(2-carboxyethyl)amino]carbonyl]phenyl]diazenyl]-2-hydroxy-benzoic acid
  • Correlated keywords
    • balsalazida balsalazido balsalazidum bolaza colazide giazo prodrug 5-ASA 5ASA antiinflammatory
  • Product Overview:
    Balsalazide is a prodrug form of 5-aminosalicylic acid (5-ASA; Item No. 70265).{48536} It is cleaved by bacterial azoreductases in the intestinal lumen to release 5-ASA. Balsalazide (600 mg/kg per day) decreases IL-2 levels and increases IL-6 levels in the serum and colonic mucosa membrane, as well as decreases micro- and macroscopic colonic damage, in a rat model of colitis induced by 2,4-dinitrochlorobenzene (DNCB).{48537} Formulations containing balsalazide have been used in the treatment of ulcerative colitis.

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