Azithromycin-d₃

Territorial Availability: Available through Bertin Technologies only in France

• Synonyms
  • (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-?-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-6-(methyl-d3)-11-[[3,4,6-trideoxy-3-(dimethylamino)-?-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one
• Correlated keywords
  • anti-biotic malaria AZM aruzilina arzomicin auricin polyketide azasite azadose azatril azee azenil azimin aziromycin azisara azithral azithrocin azitrocin azitromax aziwin aziwok azomycin aztrin CP62993 CP-62993 CP62,993 CP-62,993 durasite hemomycin macromycin macrozit sanhe setron shimen sumamed sumazid tobil tridosil tromix trozocina ultreon XZ-405 XZ405 XZ-450 XZ450 xithron xithrone zeto zi-factor zifin zistic zithromac zithromax Zithromax-IV zitrim zitrocin zitromax zythromax deuterated deuterium GC-MS GC/MS gases chromatography masses spectrometry LC-MS LC/MS isotope GCMS LCMS deuterated deuterium interleukin Streptococcus Neisseria Mycoplasma pneumonia Helicobacter Chlamydia Haemophilus Streptococcus Enterococcus TNF? IL1? IL6
• Product Overview:
  Azithromycin-d3 is intended for use as an internal standard for the quantification of azithromycin (Item No. 15004) by GC- or LC-MS. Azithromycin is a macrolide antibiotic.{22758} It is active against S. pneumoniae, S. aureus, N. gonorrhoeae, M. pneumoniae, H. pylori, C. trachomatis, and H. influenzae in vitro (MIC90s = S. pyogenes, S. pneumoniae, E. faecalis, or H. influenzae infection (ED50s = 0.78, 8.7, 12.7, and 30.3 mg/kg, respectively).{53594} It inhibits replication of severe acute respiratory coronavirus 2 (SARS-CoV-2), but not Middle East respiratory syndrome CoV (MERS-CoV), when used at concentrations of 5 and 10 µM.{57523} Azithromycin also decreases plasma levels of IL-6, TNF-?, and IL-1? and increases survival in a mouse model of LPS-induced sepsis when administered at a dose of 100 mg/kg.{53595} Formulations containing azithromycin have been used in the treatment of a variety of bacterial infections.