Azido-<wbr/>Thalidomide

Azido-Thalidomide

CAT N°: 26146
Price:

From 92.00 78.20

Azido-thalidomide is a building block in the synthesis of proteolysis-targeting chimera (PROTAC) technologies.{46112} It contains thalidomide, which is a ligand for the E3 ubiquitin ligase cereblon, and can be conjugated to alkynylated ligands for target proteins via click chemistry. Azido-thalidomide has been used in the synthesis of a SirReal-based PROTAC for the degradation of sirtuin 2 (Sirt2) in cells.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • N-(4-azidobutyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-acetamide
  • Correlated keywords
    • E-3 Sirt Azidothalidomide
  • Product Overview:
    Azido-thalidomide is a building block in the synthesis of proteolysis-targeting chimera (PROTAC) technologies.{46112} It contains thalidomide, which is a ligand for the E3 ubiquitin ligase cereblon, and can be conjugated to alkynylated ligands for target proteins via click chemistry. Azido-thalidomide has been used in the synthesis of a SirReal-based PROTAC for the degradation of sirtuin 2 (Sirt2) in cells.

We also advise you