AZD 8330

AZD 8330

CAT N°: 11588
Price:

From 92.00 78.20

AZD 8330 is a selective allosteric inhibitor of MEK1/2 (IC50 = 7 nM). It blocks phosphorylation of ERK1/2 and inhibits proliferation of certain cancer cells.{32893} AZD 8330 is orally bioavailable, inhibits ERK phosphorylation in vivo, and reduces tumor growth in a Calu-6 nude rat xenograft model.{32894}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 2-[(2-fluoro-4-iodophenyl)amino]-1,6-dihydro-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxo-3-pyridinecarboxamide
  • Correlated keywords
    • 1204531-17-8 MEK AZD8330 ARRY704 ARRY-704 MAP/ERK allosteric phosphorylation MEK1/2 Calu-6 ARRY424704
  • Product Overview:
    AZD 8330 is a selective allosteric inhibitor of MEK1/2 (IC50 = 7 nM). It blocks phosphorylation of ERK1/2 and inhibits proliferation of certain cancer cells.{32893} AZD 8330 is orally bioavailable, inhibits ERK phosphorylation in vivo, and reduces tumor growth in a Calu-6 nude rat xenograft model.{32894}

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