(+)-D-threo–PDMP (hydrochloride)
(+)-D-threo–PDMP (hydrochloride)
(+)-D-threo-PDMP is a ceramide analog and is one of the four possible stereoisomers of PDMP (Item No. 62595).{11392} (+)-D-threo-PDMP is...
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€91.00 €77.35
€91.00 €77.35
Azatadine is an antihistamine with anticholinergic and antiserotonergic activities.{25628},{52335} It is a histamine H1 receptor antagonist (Ki = 3.9 nM).{52336},{32989} Azatadine inhibits histamine- and acetylcholine-induced contractions in isolated guinea pig ilium and contractions induced by serotonin (5-HT; Item No. 14332) in isolated rat uterus (EC50s = 6.5, 10, and 14 nM, respectively).{52335} It delays the onset of dyspnea induced by aerosolized histamine, 5-HT, or acetylcholine in guinea pigs. Azatadine prevents histamine-induced lethality in guinea pigs and paw edema in mice (ED50s = 9 and 68 ?g/kg, respectively).{25628} It increases survival in guinea pig and mouse models of anaphylactic shock with 50% protective dose (PD50) values of 0.024 and 0.019 mg/kg, respectively.{52335}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 100 mg, 250 mg, 50 mg, 500 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 3978-86-7 |
| Molecular formula | C20H22N2 • 2C4H4O4 |
| Smiles | CN(CC/1)CCC1=C2C(N=CC=C3)=C3CCC4=C2C=CC=C4.OC(/C=CC(O)=O)=O.OC(/C=CC(O)=O)=O, CN(CC/1)CCC1=C2C(N=CC=C3)=C3CCC4=C2C=CC=C4.OC(/C=CC(O)=O)=O.OC(/C=CC(O)=O)=O, CN(CC/1)CCC1=C2C(N=CC=C3)=C3CCC4=C2C=CC=C4.OC(/C=CC(O)=O)=O.OC(/C=CC(O)=O)=O, CN(CC/1)CCC1=C2C(N=CC=C3)=C3CCC4=C2C=CC=C4.OC(/C=CC(O)=O)=O.OC(/C=CC(O)=O)=O |
| Molecular weight | 522,6 |
| Custom code | 2933.39 |
| Formulation | A solid |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
Cayman Chemical’s mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.
Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
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