Azamulin

Azamulin

CAT N°: 18748
Price:

From 68.00 57.80

Azamulin is a selective, irreversible inhibitor of cytochrome P450 (CYP) 3A isoforms (IC50 values range from 26 to 240 nM for CYP3A4 and CYP3A4/5 from different sources).{30387} It is at least 50-fold less potent against CYP2J2 and 100-fold less effective against all other CYP isoforms.{30387} Azamulin potently blocks the hydroxylation of testosterone and midazolam by CYP3A4.{30387,30386}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (3aS,4R,5S,6R,8R,9R,9aR,10R)-6-ethyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester 2-[(3-amino-1H-1,2,4-triazol-5-yl)thio]-acetic acid
  • Correlated keywords
    • 83203-43-4 CYP3A CYP-3A cytochrome P450 TDM 85530 TDM85-530 TDM85530 SA85530b SA 85530-b SA85530-b
  • Product Overview:
    Azamulin is a selective, irreversible inhibitor of cytochrome P450 (CYP) 3A isoforms (IC50 values range from 26 to 240 nM for CYP3A4 and CYP3A4/5 from different sources).{30387} It is at least 50-fold less potent against CYP2J2 and 100-fold less effective against all other CYP isoforms.{30387} Azamulin potently blocks the hydroxylation of testosterone and midazolam by CYP3A4.{30387,30386}

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