AZ 3146

AZ 3146

CAT N°: 19991
Price:

159.00 135.15

AZ 3146 is an inhibitor of the monopolar spindle 1 (Mps1) checkpoint kinase (IC50 = 35 nM).{33103} It displays selectivity over 46 other kinases including Cdk1 and Aurora kinase B.{33103} It has been shown to inhibit the recruitment of Mad1, Mad2, and centromere protein E (CENP-E) to kinetochores.{33103} AZ 3146 can be used with GSK923295 (Item No. 18389), an inhibitor of CENP-E, to generate aneuploidy in cells.{31964}

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