Aszonapyrone A

Aszonapyrone A

CAT N°: 29940
Price:

From 322.00 273.70

Aszonapyrone A is a meroditerpene fungal metabolite that has been found in Neosartorya and has diverse biological activities.{41303,41304,41720} It inhibits the growth of MCF-7, NCI H460, and A375-C5 cancer cells (GI50s = 13.6, 11.6, and 10.2 ?M, respectively).{41303} Aszonapyrone A is active against multidrug-resistant isolates of S. aureus, E. faecalis, and E. faecium (MICs = 8, 16, and 16 ?g/ml, respectively) and inhibits S. aureus biofilm formation.{41304} It is also active against P. falciparum in vitro (IC50 = 1.34 ?g/ml).{41720}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 3-[[(1R,4aS,4bR,7S,8aR,10aS)-7-(acetyloxy)tetradecahydro-4b,8,8,10a-tetramethyl-2-methylene-1-phenanthrenyl]methyl]-4-hydroxy-6-methyl-2H-pyran-2-one
  • Correlated keywords
    • MCF7 NCIH460 H 460 A375C5 A 375 C 5 Staphylococcus Enterococcus Plasmodium Acetylaszonapyrone
  • Product Overview:
    Aszonapyrone A is a meroditerpene fungal metabolite that has been found in Neosartorya and has diverse biological activities.{41303,41304,41720} It inhibits the growth of MCF-7, NCI H460, and A375-C5 cancer cells (GI50s = 13.6, 11.6, and 10.2 ?M, respectively).{41303} Aszonapyrone A is active against multidrug-resistant isolates of S. aureus, E. faecalis, and E. faecium (MICs = 8, 16, and 16 ?g/ml, respectively) and inhibits S. aureus biofilm formation.{41304} It is also active against P. falciparum in vitro (IC50 = 1.34 ?g/ml).{41720}

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