24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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From €65.00 €55.25
Artemisinic acid is a sesquiterpene that has been isolated from A. annua.{41903} It has been used in the synthesis of the antimalarial agent artemisinin (Item No. 11816).{41904} Artemisinic acid (50-400 µM) decreases triglyceride levels and glycerol-3-phosphate dehydrogenase (GPDH) activity in human adipose tissue-derived mesenchymal stem cells (hAMSCs) in a dose-dependent manner and inhibits adipocyte differentiation when used at a concentration of 200 µM.{41905} It reduces mRNA expression and protein levels of C/EBP?, C/EBP?, and PPAR? as well as the ratio of phosphorylated JNK to JNK in hAMSCs. Artemisinic acid also decreases C/EBP? and HMG-CoA reductase mRNA expression and inhibits cholesterol synthesis and melanogenesis in human epidermal melanocytes.{41906}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 10 mg, 100 mg, 25 mg, 50 mg |
|---|---|
| Shipping | dry ice |
| CAS number | 80286-58-4 |
| Molecular formula | C15H22O2 |
| Smiles | CC1=C[C@@]2([H])[C@](CC1)([H])[C@H](C)CC[C@H]2C(C(O)=O)=C |
| Molecular weight | 234,3 |
| Custom code | 2902.90 |
| Formulation | A crystalline solid |
| Purity | ≥98% |
| UNSPSC code | 12352100 |
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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
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