Aristolochic Acid B

Aristolochic Acid B

CAT N°: 28504
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Aristolochic acid B is an alkaloid that has been found in Aristolochia with mutagenic activity.{45593} It forms DNA adducts under anaerobic conditions in vitro when used at a concentration of 0.4 mM. Oral administration of aristolochic acid B (0.03 mmol/kg) induces bladder, forestomach, and kidney DNA adduct formation in rats. Aristolochic acid B reduces body weight and urine concentrations of sodium, potassium, and calcium, enlarges the liver and kidneys, and increases blood concentrations of hemoglobin and hematocrit in rats.{45594}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 6-nitro-phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid
  • Correlated keywords
    • 79468-63-6 AA-II AAII
  • Product Overview:
    Aristolochic acid B is an alkaloid that has been found in Aristolochia with mutagenic activity.{45593} It forms DNA adducts under anaerobic conditions in vitro when used at a concentration of 0.4 mM. Oral administration of aristolochic acid B (0.03 mmol/kg) induces bladder, forestomach, and kidney DNA adduct formation in rats. Aristolochic acid B reduces body weight and urine concentrations of sodium, potassium, and calcium, enlarges the liver and kidneys, and increases blood concentrations of hemoglobin and hematocrit in rats.{45594}

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