(+)-D-threo–PDMP (hydrochloride)
(+)-D-threo–PDMP (hydrochloride)
(+)-D-threo-PDMP is a ceramide analog and is one of the four possible stereoisomers of PDMP (Item No. 62595).{11392} (+)-D-threo-PDMP is...
€707.00
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€359.00 €305.15
€359.00 €305.15
Arginine vasotocin is a nonapeptide hormone agonist of the AVT receptor (EC50 = 13 nM for eliciting membrane currents in X. laevis oocytes).{36550} Arginine vasotocin is synthesized in the pineal recess and subcommissural organ by ependymal cells and released into the cerebrospinal fluid.{36555} It inhibits the induction of sleep and release of hypothalamic releasing and inhibiting hormones. Arginine vasotocin stimulates glycogen phosphorylase ? activity and incorporation of phosphate into phosphatidylinositol in rat hepatocytes (EC50s = 0.5 nM and 6.3 nM, respectively).{36551} Following a two-minute pulse of arginine vasotocin (1 ?M) to neurons isolated from rat suprachiasmatic nuclei, 40.6% of neurons show an increase in firing rate with 11% of the activated neurons responding only to arginine vasotocin and not argipressin (Item No. 24154).{36553} Arginine vasotocin (0.1 ?g, i.c.v.) activates sexual behavior in male newts and increases the number of clasps per male from saline control levels of 0.6 to 2.9 in an eight-hour period.{36552} In rainbow trout, arginine vasotocin (0.1 ng/g, i.c.v.) reduces food intake by over 95% and, after eight hours, increases cortisol and glucose levels by 89% and 27%, respectively.{36554}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 5 mg |
|---|---|
| Shipping | dry ice |
| Molecular formula | C43H67N15O12S2 • XCF3COOH |
| Smiles | NC(CNC([C@H](CCCNC(N)=N)NC([C@@H]1CCCN1C([C@@H](N2)CSSC[C@H](N[H])C(N[C@H](C(N[C@]([C@H](CC)C)([H])C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(N)=O)C2=O)=O)=O)=O)CC3=CC=C(O)C=C3)=O)=O)=O)=O)=O.FC(F)(C(O)=O)F |
| Molecular weight | 1050,2 |
| Formulation | A lyophilized powder |
| Purity | ≥95% |
| Custom code | 3504.00 |
| UNSPSC code | 12352100 |
Cayman Chemical’s mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.
Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.
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