AR-C 155858

AR-C 155858

CAT N°: 14884
Price:

365.00 310.25

AR-C 155858 is an inhibitor of monocarboxylate transporter 1 (MCT1) and MCT2 (Kis = 2.3 and Xenopus oocytes expressing the human receptors).{48632} It is selective for MCT1 and MCT2 over MCT4 (Ki = >10 ?M). AR-C 155858 inhibits L-lactate uptake in and proliferation of murine 4T1 breast cancer cells (IC50s = 25 and 20.2 nM, respectively).{48633}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 6-[(3,5-dimethyl-1H-pyrazol-4-yl)methyl]-5-[[(4S)-4-hydroxy-2-isoxazolidinyl]carbonyl]-3-methyl-1-(2-methylpropyl)-thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione
  • Correlated keywords
    • MCT 1 2 4 ARC 155858 ARC155858 C155858 T1 T 1
  • Product Overview:
    AR-C 155858 is an inhibitor of monocarboxylate transporter 1 (MCT1) and MCT2 (Kis = 2.3 and Xenopus oocytes expressing the human receptors).{48632} It is selective for MCT1 and MCT2 over MCT4 (Ki = >10 ?M). AR-C 155858 inhibits L-lactate uptake in and proliferation of murine 4T1 breast cancer cells (IC50s = 25 and 20.2 nM, respectively).{48633}

We also advise you