Apiin

Apiin

CAT N°: 34596
Price:

From 66.00 56.10

Apiin is a polyketide synthase-derived flavonoid glycoside that has been found in A. graveolens and has diverse biological activities.{63166,61488,63167,63168} It inhibits Aurora B kinase in a cell-free assay using the human enzyme (IC50 = 12.14 µM).{61488} Apiin (10 and 50 µg/ml) inhibits LPS-induced increases in nitric oxide (NO) release and inducible nitric oxide synthase (iNOS) levels in J774.A1 macrophages.{63167} It scavenges DPPH (Item No. 14805), superoxide, and hydroxyl radicals (IC50s = 68, 390, and 48 µg/ml, respectively), as well as increases the levels of superoxide dismutase (SOD) and catalase in mouse serum, brain, heart, liver, and kidney when administered at a dose of 50 mg/kg.{63168}

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