Amyloid-? (1-42) Peptide (trifluoroacetate salt)

Amyloid-? (1-42) Peptide (trifluoroacetate salt)

CAT N°: 20574
Price:

From €276.00 €234.60

Amyloid-? (1-42) (A?42) is a neurotoxic 42-amino acid protein fragment found in amyloid plaques in postmortem cerebral cortex from patients with Alzheimer’s disease.{10614,42695,54362} Aggregation of A?42 results in the formation of neurotoxic fibrils or globular oligomers.{10614} A?42 accumulates in the brain of many transgenic mouse models of Alzheimer’s disease and, in many models, the onset of amyloid deposition positively correlates with deficits in spatial learning and memory.{54363}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • L-?-aspartyl-L-alanyl-L-?-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-?-aspartyl-L-serylglycyl-L-tyrosyl-L-?-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-?-glutamyl-L-?-aspartyl-L-valylglycyl-L-seryl-L-asparaginyl-L-lysylglycyl-L-alanyl-L-isoleucyl-L-isoleucylglycyl-L-leucyl-L-methionyl-L-valylglycylglycyl-L-valyl-L-valyl-L-isoleucyl-L-alanine, trifluoroacetate salt
  • Correlated keywords
    • 136250-78-7 143044-07-9 281660-50-2 amyloid-?42 A?-(1-42) A? 42 Abeta-1-42 107761-42-2 post-mortem
  • Product Overview:
    Amyloid-? (1-42) (A?42) is a neurotoxic 42-amino acid protein fragment found in amyloid plaques in postmortem cerebral cortex from patients with Alzheimer’s disease.{10614,42695,54362} Aggregation of A?42 results in the formation of neurotoxic fibrils or globular oligomers.{10614} A?42 accumulates in the brain of many transgenic mouse models of Alzheimer’s disease and, in many models, the onset of amyloid deposition positively correlates with deficits in spatial learning and memory.{54363}

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