Amyloid-? (1-40) Peptide (human) (trifluoro<wbr/>acetate salt)

Amyloid-? (1-40) Peptide (human) (trifluoroacetate salt)

CAT N°: 21617
Price:

From €200.00 €170.00

Amyloid-? (1-40) (A?40) peptide is a 40-residue protein fragment of A?42 (Item No. 20574), a neurotoxic peptide found in amyloid plaques in postmortem cerebral cortex from patients with Alzheimer’s disease.{10614,42695} A?40 is more abundant, less neurotoxic, and does not form oligomers as easily as A?42.{33895,33896} A?40 inhibits in vitro fibrillization of A?42 in a concentration-dependent manner.{33898} It also inhibits A?42-induced cell death in cultured rat embryonic cortical neurons in a concentration-dependent manner. A?40 prevents A?42-induced increases in the number of GFAP-positive astrocytes in rat entorhinal cortex.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • L-?-aspartyl-L-alanyl-L-?-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-?-aspartyl-L-serylglycyl-L-tyrosyl-L-?-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-?-glutamyl-L-?-aspartyl-L-valylglycyl-L-seryl-L-asparaginyl-L-lysylglycyl-L-alanyl-L-isoleucyl-L-isoleucylglycyl-L-leucyl-L-methionyl-L-valylglycylglycyl-L-valyl-L-valine, trifluoroacetate salt
  • Correlated keywords
    • 149531-25-9 257942-44-2 281660-52-4 292605-71-1 1802086-32-3 b-amyloid Ab40 Ab42 ab 40 42 A?40 131438-79-4
  • Product Overview:
    Amyloid-? (1-40) (A?40) peptide is a 40-residue protein fragment of A?42 (Item No. 20574), a neurotoxic peptide found in amyloid plaques in postmortem cerebral cortex from patients with Alzheimer’s disease.{10614,42695} A?40 is more abundant, less neurotoxic, and does not form oligomers as easily as A?42.{33895,33896} A?40 inhibits in vitro fibrillization of A?42 in a concentration-dependent manner.{33898} It also inhibits A?42-induced cell death in cultured rat embryonic cortical neurons in a concentration-dependent manner. A?40 prevents A?42-induced increases in the number of GFAP-positive astrocytes in rat entorhinal cortex.

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