Amorolfine (hydro<wbr/>chloride)

Amorolfine (hydrochloride)

CAT N°: 26077
Price:

From 92.00 78.20

Amorolfine is an antifungal.{41490} It is active against isolates of T. rubrum, T. mentagrophytes, and C. albicans (MIC90s = 4-15, 4-60, and ?30-500 ng/ml, respectively). It inhibits the growth of T. mentagrophytes and T. rubrum by 33.7 and 38.5%, respectively, in an in vitro bovine hoof model of onychomycosis.{36951} Amorolfine also decreases the fungal burden in a rabbit model of onychomycosis when used as a 5% nail lacquer.{36952} Formulations containing amorolfine have been used in the treatment of fungal infections of the toe- or fingernails.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (2R,6S)-rel-4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-morpholine, monohydrochloride
  • Correlated keywords
    • 78613-35-1 Ro14-4767/002 anti-fungal Trichophyton Candida
  • Product Overview:
    Amorolfine is an antifungal.{41490} It is active against isolates of T. rubrum, T. mentagrophytes, and C. albicans (MIC90s = 4-15, 4-60, and ?30-500 ng/ml, respectively). It inhibits the growth of T. mentagrophytes and T. rubrum by 33.7 and 38.5%, respectively, in an in vitro bovine hoof model of onychomycosis.{36951} Amorolfine also decreases the fungal burden in a rabbit model of onychomycosis when used as a 5% nail lacquer.{36952} Formulations containing amorolfine have been used in the treatment of fungal infections of the toe- or fingernails.

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