Amorfrutin B

Amorfrutin B

CAT N°: 19618
Price:

249.00 211.65

Amorfrutin B is a partial agonist of the peroxisome proliferator-activated receptor ? (PPAR?; Ki = 19 nM and EC50 = 73 nM) that was first isolated from A. fruticosa.{31276} It binds to PPAR? and PPAR?/? with Ki values of 2.6 and 1.7 µM, respectively.{31276} In insulin-resistant mice, 100 mg/kg/day amorfrutin B is reported to improve insulin sensitivity, glucose tolerance, and plasma lipid concentrations after two weeks of treatment.{31276}

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