Alisol A

Alisol A

CAT N°: 34050
Price:

From 182.00 154.70

Alisol A is a terpenoid that has been found in A. orientale and has diverse biological activities.{58513,58514,58515,58516} It inhibits the secretion of hepatitis B virus (HBV) surface antigen in HBV-infected 2.2.15 cells (IC50 = 39 µM).{58514} Alisol A (20 and 40 µM) induces cell cycle arrest at the G0/G1 phase and autophagy in MDA-MB-231 human breast cancer cells.{58515} It reduces hepatic steatosis and increases in plasma triglyceride, total cholesterol, LDL-C, and HDL-C levels in a mouse model of high-fat diet-induced obesity when administered at a dose of 100 mg/kg per day.{58516} Alisol A decreases blood glucose and insulin levels in intraperitoneal glucose and insulin tolerance tests, respectively, in the same model.

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