Aliskiren (hemi<wbr>fumarate)

Aliskiren (hemifumarate)

CAT N°: 19640
Price:

48.00 40.80

Aliskiren is a nonpeptide inhibitor of renin (IC50 = 0.6 nM for the human enzyme).{31535} Aliskiren (10 and 30 mg/kg per day) reduces blood pressure and prevents albuminuria in renin-overexpressing TG(mRen-2)27 rats in a model of streptozotocin-induced diabetes.{61205} It also reduces cardiac hypertrophy and fibrosis induced by heart pressure overload in mice.{61206} Formulations containing aliskiren have been used in the treatment of hypertension.

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