Alfuzosin (hydro<wbr>chloride)

Alfuzosin (hydrochloride)

CAT N°: 13648
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From 66.00 56.10

Alfuzosin is a post-synaptic ?1-adrenergic receptor antagonist commonly used to improve lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH).{18261,18269} It displays high-affinity with non-selectivity for the three known human ?1 adrenoceptors (pKi = 8.0, 8.0, and 8.5 for ?1A, ?1B, and ?1D, respectively).{18268} Consistent with a role for ?1 adrenoceptors in mediating contraction of smooth muscle, alfuzosin was first described as having anti-hypertensive effects with peripheral vasodilator properties.{18261} In patients with BPH, alfuzosin increases mean urinary flow rate and decreases residual volume.{18269} Alfuzosin produces minimal vasodilatory and sexual function side effects.{18262,18266,18267}

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